GTBP Monoclonal Antibody

簡(jiǎn)要描述：GTBP Monoclonal Antibody
宿主: Monoclonal, Mouse
反應性: Human
應用: WB;ELISA

產(chǎn)品型號： YP-Ab-00068

所屬分類(lèi)：單克隆抗體

更新時(shí)間：2023-10-26

詳細說(shuō)明：

GTBP Monoclonal Antibody

抗體，也叫免疫球蛋白（Ig），是一種能特異性結合抗原的糖蛋白，而抗原是在易感染動(dòng)物體內引發(fā)抗體產(chǎn)生的物質(zhì)。在體內，抗體是由于外源性分子的侵襲而產(chǎn)生的?？贵w以一個(gè)或者多個(gè)Y字形單體存在，每個(gè)Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據它們的分子量大小來(lái)命名的。Y字形結構的頂端是可變區，為抗原結合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結構上的差異），每一個(gè)抗體的重鏈則決定了它的類(lèi)或型。

產(chǎn)品詳情

GTBP Monoclonal Antibody detects endogenous levels of GTBP protein.

免疫原詳細信息

Purified recombinant fragment of human GTBP expressed in E. Coli.

相關(guān)試劑

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

背景

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

天津俊達生物科技有限公司，是從事實(shí)驗室耗材銷(xiāo)售的現代化生物科技企業(yè)，公司本著(zhù)“誠信為本，互利共贏(yíng)"的核心價(jià)值觀(guān)，秉承“以市場(chǎng)為導向，提供服務(wù)"的宗旨為各大院校、科研單位、第三方實(shí)驗室檢測機構等提供的產(chǎn)品和服務(wù)。目前公司主要經(jīng)營(yíng)分子生物學(xué)、細胞生物學(xué)、免疫學(xué)等生物學(xué)產(chǎn)品，多種實(shí)驗室耗材歡迎垂詢(xún)！

備注：圖片僅供參考。僅供科研，不可用于臨床。